An unusual case of basal cell carcinoma of the vulva with lung metastases
Identifieur interne : 001428 ( Main/Exploration ); précédent : 001427; suivant : 001429An unusual case of basal cell carcinoma of the vulva with lung metastases
Auteurs : Ga Watson [Irlande (pays)] ; D. Kelly [Irlande (pays)] ; L. Prior [Irlande (pays)] ; E. Stanley [Irlande (pays)] ; O. Maceneaney [Irlande (pays)] ; T. Walsh [Irlande (pays)] ; Cm Kelly [Irlande (pays)]Source :
- Gynecologic Oncology Reports [ 2352-5789 ] ; 2016.
Abstract
Basal cell carcinoma (BCC) is the most common non-melanomatous skin cancer, typically arising in sun-exposed areas such as the head and neck. Defective signaling through the Hedgehog (HH) signaling pathway forms the molecular basis for BCC. Surgery remains the mainstay of treatment. Basal cell carcinoma of the genital tract is rare as is metastatic BCC. We report a case of metastatic BCC in a young woman with previously resected vulval BCC presenting six years later with inguinal nodal recurrence and multiple lung metastases.
Url:
DOI: 10.1016/j.gore.2016.10.005
PubMed: 27830172
PubMed Central: 5094149
Affiliations:
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Prior</name><affiliation wicri:level="1"><nlm:aff id="af0005">Department of Medical Oncology, Mater Misericordiae University Hospital, Eccles St., Dublin 7, Ireland</nlm:aff><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>Department of Medical Oncology, Mater Misericordiae University Hospital, Eccles St., Dublin 7</wicri:regionArea><wicri:noRegion>Dublin 7</wicri:noRegion></affiliation></author><author><name sortKey="Stanley, E" sort="Stanley, E" uniqKey="Stanley E" first="E" last="Stanley">E. 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Maceneaney</name><affiliation wicri:level="1"><nlm:aff id="af0015">Department of Pathology, Mater Misericordiae University Hospital, Eccles St., Dublin 7, Ireland</nlm:aff><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>Department of Pathology, Mater Misericordiae University Hospital, Eccles St., Dublin 7</wicri:regionArea><wicri:noRegion>Dublin 7</wicri:noRegion></affiliation></author><author><name sortKey="Walsh, T" sort="Walsh, T" uniqKey="Walsh T" first="T" last="Walsh">T. Walsh</name><affiliation wicri:level="1"><nlm:aff id="af0020">Department of Gynaecology, Mater Misericordiae University Hospital, Eccles St., Dublin 7, Ireland</nlm:aff><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>Department of Gynaecology, Mater Misericordiae University Hospital, Eccles St., Dublin 7</wicri:regionArea><wicri:noRegion>Dublin 7</wicri:noRegion></affiliation></author><author><name sortKey="Kelly, Cm" sort="Kelly, Cm" uniqKey="Kelly C" first="Cm" last="Kelly">Cm Kelly</name><affiliation wicri:level="1"><nlm:aff id="af0005">Department of Medical Oncology, Mater Misericordiae University Hospital, Eccles St., Dublin 7, Ireland</nlm:aff><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>Department of Medical Oncology, Mater Misericordiae University Hospital, Eccles St., Dublin 7</wicri:regionArea><wicri:noRegion>Dublin 7</wicri:noRegion></affiliation></author></analytic><series><title level="j">Gynecologic Oncology Reports</title><idno type="eISSN">2352-5789</idno><imprint><date when="2016">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Basal cell carcinoma (BCC) is the most common non-melanomatous skin cancer, typically arising in sun-exposed areas such as the head and neck. Defective signaling through the Hedgehog (HH) signaling pathway forms the molecular basis for BCC. Surgery remains the mainstay of treatment. Basal cell carcinoma of the genital tract is rare as is metastatic BCC. We report a case of metastatic BCC in a young woman with previously resected vulval BCC presenting six years later with inguinal nodal recurrence and multiple lung metastases.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Rubin, A I" uniqKey="Rubin A">A.I. Rubin</name></author><author><name sortKey="Chen, E H" uniqKey="Chen E">E.H. Chen</name></author><author><name sortKey="Ratner, D" uniqKey="Ratner D">D. Ratner</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jacob, A" uniqKey="Jacob A">A. Jacob</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fleury, A C" uniqKey="Fleury A">A.C. 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Gutzmer</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Irlande (pays)</li></country></list><tree><country name="Irlande (pays)"><noRegion><name sortKey="Watson, Ga" sort="Watson, Ga" uniqKey="Watson G" first="Ga" last="Watson">Ga Watson</name></noRegion><name sortKey="Kelly, Cm" sort="Kelly, Cm" uniqKey="Kelly C" first="Cm" last="Kelly">Cm Kelly</name><name sortKey="Kelly, D" sort="Kelly, D" uniqKey="Kelly D" first="D" last="Kelly">D. Kelly</name><name sortKey="Maceneaney, O" sort="Maceneaney, O" uniqKey="Maceneaney O" first="O" last="Maceneaney">O. Maceneaney</name><name sortKey="Prior, L" sort="Prior, L" uniqKey="Prior L" first="L" last="Prior">L. Prior</name><name sortKey="Stanley, E" sort="Stanley, E" uniqKey="Stanley E" first="E" last="Stanley">E. Stanley</name><name sortKey="Walsh, T" sort="Walsh, T" uniqKey="Walsh T" first="T" last="Walsh">T. 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